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EGR2-mediated regulation of m(6)A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization
Emerging discoveries of dynamic and reversible N6-methyladenosine (m(6)A) modification on RNA in mammals have revealed the key roles of the modification in human tumorigenesis. As known m(6)A readers, insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) are upregulated in most cancers and me...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8322060/ https://ncbi.nlm.nih.gov/pubmed/34326314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04038-3 |
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