NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by downregulating TCEB1 mRNA via Staufen1-mediated mRNA decay

Previous study demonstrated that most long non-coding RNAs (lncRNAs) function as competing endogenous RNAs or molecular sponges to negatively modulate miRNA and regulate tumor development. However, the molecular mechanisms of lncRNAs in cancer are not fully understood. Our study describes the role o...

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Udgivet i:Oncogene
Main Authors: Zhao, Lin, Jiang, Longyang, Zhang, Ming, Zhang, Qiang, Guan, Qiutong, Li, Yalun, He, Miao, Zhang, Jingdong, Wei, Minjie
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321898/
https://ncbi.nlm.nih.gov/pubmed/34163032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01900-8
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