On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice

Myoglobin (Mb) regulates O(2) bioavailability in muscle and heart as the partial pressure of O(2) (Po(2)) drops with increased tissue workload. Globin proteins also modulate cellular NO pools, “scavenging” NO at higher Po(2) and converting NO(2)(−) to NO as Po(2) falls. Myoglobin binding of fatty ac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Endocrinol Metab
Prif Awduron: Blackburn, Michael L., Wankhade, Umesh D., Ono-Moore, Kikumi D., Chintapalli, Sree V., Fox, Renee, Rutkowsky, Jennifer M., Willis, Brandon J., Tolentino, Todd, Lloyd, K. C. Kent, Adams, Sean H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321818/
https://ncbi.nlm.nih.gov/pubmed/33969705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00662.2020
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