On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice

Myoglobin (Mb) regulates O(2) bioavailability in muscle and heart as the partial pressure of O(2) (Po(2)) drops with increased tissue workload. Globin proteins also modulate cellular NO pools, “scavenging” NO at higher Po(2) and converting NO(2)(−) to NO as Po(2) falls. Myoglobin binding of fatty ac...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Blackburn, Michael L., Wankhade, Umesh D., Ono-Moore, Kikumi D., Chintapalli, Sree V., Fox, Renee, Rutkowsky, Jennifer M., Willis, Brandon J., Tolentino, Todd, Lloyd, K. C. Kent, Adams, Sean H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321818/
https://ncbi.nlm.nih.gov/pubmed/33969705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00662.2020
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