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N(6)-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses

Among over 150 distinct RNA modifications, N(6)-methyladenosine (m(6)A) and adenosine-to-inosine (A-to-I) RNA editing represent 2 of the most studied modifications on mammalian mRNAs. Although both modifications occur on adenosine residues, knowledge on potential functional crosstalk between these 2...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Terajima, Hideki, Lu, Mijia, Zhang, Linda, Cui, Qi, Shi, Yanhong, Li, Jianrong, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320976/
https://ncbi.nlm.nih.gov/pubmed/34324489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001292
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