RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages

ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. Here, we have determined the role of ADAR1 as a regulator of...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Pujantell, Maria, Riveira-Muñoz, Eva, Badia, Roger, Castellví, Marc, Garcia-Vidal, Edurne, Sirera, Guillem, Puig, Teresa, Ramirez, Cristina, Clotet, Bonaventura, Esté, José A., Ballana, Ester
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645456/
https://ncbi.nlm.nih.gov/pubmed/29042669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13580-0
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