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RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages
ADAR1-dependent A-to-I editing has recently been recognized as a key process for marking dsRNA as self, therefore, preventing innate immune activation and affecting the development and resolution of immune-mediated diseases and infections. Here, we have determined the role of ADAR1 as a regulator of...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5645456/ https://ncbi.nlm.nih.gov/pubmed/29042669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13580-0 |
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