The Second Oncogenic Hit Determines the Cell Fate of ETV6-RUNX1 Positive Leukemia

ETV6-RUNX1 is almost exclusively associated with childhood B-cell acute lymphoblastic leukemia (B-ALL), but the consequences of ETV6-RUNX1 expression on cell lineage decisions during B-cell leukemogenesis are completely unknown. Clinically silent ETV6-RUNX1 preleukemic clones are frequently found in...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Rodríguez-Hernández, Guillermo, Casado-García, Ana, Isidro-Hernández, Marta, Picard, Daniel, Raboso-Gallego, Javier, Alemán-Arteaga, Silvia, Orfao, Alberto, Blanco, Oscar, Riesco, Susana, Prieto-Matos, Pablo, García Criado, Francisco Javier, García Cenador, María Begoña, Hock, Hanno, Enver, Tariq, Sanchez-Garcia, Isidro, Vicente-Dueñas, Carolina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320889/
https://ncbi.nlm.nih.gov/pubmed/34336858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.704591
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