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Co-culture with mouse embryonic fibroblasts improves maintenance of metabolic function of human small hepatocyte progenitor cells

Derivation and culture of small hepatocyte progenitor cells (SHPCs) capable of proliferating in vitro has been described in rodents and recently in humans. These cells are capable of engrafting in injured livers, however, they display de-differentiated morphology and reduced xenobiotic metabolism ac...

詳細記述

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書誌詳細
出版年:Curr Res Toxicol
主要な著者: Sengupta, Srikumar, Johnson, Brian, Seirup, Morten, Ardalani, Hamisha, Duffin, Bret, Barrett-Wilt, Gregory A., Stewart, Ron, Thomson, James A.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320630/
https://ncbi.nlm.nih.gov/pubmed/34345838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crtox.2020.08.001
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