IL-33 Drives Expansion of Type 2 Innate Lymphoid Cells and Regulatory T Cells and Protects Mice From Severe, Acute Colitis

The hallmarks of inflammatory bowel disease are mucosal damage and ulceration, which are known to be high-risk conditions for the development of colorectal cancer. Recently, interleukin (IL)-33 and its receptor ST2 have emerged as critical modulators in inflammatory disorders. Even though several st...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Ngo Thi Phuong, Nhi, Palmieri, Vittoria, Adamczyk, Alexandra, Klopfleisch, Robert, Langhorst, Jost, Hansen, Wiebke, Westendorf, Astrid M., Pastille, Eva
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320374/
https://ncbi.nlm.nih.gov/pubmed/34335571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.669787
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