The IL-33/ST2 pathway shapes the regulatory T cell phenotype to promote intestinal cancer

The composition of immune infiltrates strongly affects the prognosis of patients with colorectal cancer (CRC). Interleukin (IL)-33 and regulatory T cells (Tregs) in the tumor microenvironment have been separately implicated in CRC; however their contribution to intestinal carcinogenesis is still con...

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Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Pastille, Eva, Wasmer, Marie-Hélène, Adamczyk, Alexandra, Vu, Vivian P., Mager, Lukas F., Phuong, Nhi Ngo Thi, Palmieri, Vittoria, Simillion, Cedric, Hansen, Wiebke, Kasper, Stefan, Schuler, Martin, Muggli, Beat, McCoy, Kathy D., Buer, Jan, Zlobec, Inti, Westendorf, Astrid M., Krebs, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group US 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746527/
https://ncbi.nlm.nih.gov/pubmed/31165767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0176-y
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