Paclitaxel increases axonal localization and vesicular trafficking of Na(v)1.7

The microtubule-stabilizing chemotherapy drug paclitaxel (PTX) causes dose-limiting chemotherapy-induced peripheral neuropathy (CIPN), which is often accompanied by pain. Among the multifaceted effects of PTX is an increased expression of sodium channel Na(v)1.7 in rat and human sensory neurons, enh...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Brain
Päätekijät: Akin, Elizabeth J, Alsaloum, Matthew, Higerd, Grant P, Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B, Waxman, Stephen G, Dib-Hajj, Sulayman D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2021
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320304/
https://ncbi.nlm.nih.gov/pubmed/33734317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab113
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