Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats

Neuronal aggregates of misfolded alpha-synuclein protein are found in the brain and periphery of patients with Parkinson’s disease. Braak and colleagues have hypothesized that the initial formation of misfolded alpha-synuclein may start in the gut, and then spread to the brain via peripheral autonom...

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Dades bibliogràfiques
Publicat a:Brain
Autors principals: Van Den Berge, Nathalie, Ferreira, Nelson, Mikkelsen, Trine Werenberg, Alstrup, Aage Kristian Olsen, Tamgüney, Gültekin, Karlsson, Páll, Terkelsen, Astrid Juhl, Nyengaard, Jens Randel, Jensen, Poul Henning, Borghammer, Per
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320301/
https://ncbi.nlm.nih.gov/pubmed/33880502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab061
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