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Resveratrol protects human nucleus pulposus cells from degeneration by blocking IL-6/JAK/STAT3 pathway

BACKGROUND: Nucleus pulposus cells’ (NPCs’) degeneration is mainly responsible for the intervertebral disc degeneration (IDD), which is closely related to inflammatory response. Among the major proinflammatory factors that are related to NPCs’ degeneration, interleukin-6 (IL-6) and its downstream JA...

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Bibliografski detalji
Izdano u:Eur J Med Res
Glavni autori: Wu, Cenhao, Ge, Jun, Yang, Ming, Yan, Qi, Wang, Yingjie, Yu, Hao, Yang, Huilin, Zou, Jun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320225/
https://ncbi.nlm.nih.gov/pubmed/34321087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-021-00555-1
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