Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation

Synaptic structural plasticity, key to long-term memory storage, requires translation of localized RNAs delivered by long-distance transport from the neuronal cell body. Mechanisms and regulation of this system remain elusive. Here, we explore the roles of KIF5C and KIF3A, two members of kinesin sup...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Swarnkar, Supriya, Avchalumov, Yosef, Espadas, Isabel, Grinman, Eddie, Liu, Xin-an, Raveendra, Bindu L., Zucca, Aya, Mediouni, Sonia, Sadhu, Abhishek, Valente, Susana, Page, Damon, Miller, Kyle, Puthanveettil, Sathyanarayanan V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319835/
https://ncbi.nlm.nih.gov/pubmed/34260917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109369
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