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Activity-regulated synaptic targeting of lncRNA ADEPTR mediates structural plasticity by localizing Sptn1 and AnkB in dendrites

Activity-dependent structural plasticity at the synapse requires specific changes in the neuronal transcriptome. While much is known about the role of coding elements in this process, the role of the long noncoding transcriptome remains elusive. Here, we report the discovery of an intronic long nonc...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Grinman, Eddie, Nakahata, Yoshihisa, Avchalumov, Yosef, Espadas, Isabel, Swarnkar, Supriya, Yasuda, Ryohei, Puthanveettil, Sathyanarayanan V.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051873/
https://ncbi.nlm.nih.gov/pubmed/33863727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf0605
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