Cell fate analysis of zone 3 hepatocytes in liver injury and tumorigenesis

BACKGROUND & AIMS: Liver lobules are typically subdivided into 3 metabolic zones: zones 1, 2, and 3. However, the contribution of zonal differences in hepatocytes to liver regeneration, as well as to carcinogenic susceptibility, remains unclear. METHODS: We developed a new method for sustained g...

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Vydáno v:JHEP Rep
Hlavní autoři: Kurosaki, Shigeyuki, Nakagawa, Hayato, Hayata, Yuki, Kawamura, Satoshi, Matsushita, Yuki, Yamada, Tomoharu, Uchino, Koji, Hayakawa, Yoku, Suzuki, Nobumi, Hata, Masahiro, Tsuboi, Mayo, Kinoshita, Hiroto, Tanaka, Yasuo, Nakatsuka, Takuma, Hirata, Yoshihiro, Tateishi, Keisuke, Koike, Kazuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319533/
https://ncbi.nlm.nih.gov/pubmed/34345813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2021.100315
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