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Portal hypertension in cirrhosis: Pathophysiological mechanisms and therapy

Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), frequently arising from chronic liver diseases. Ext...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: Iwakiri, Yasuko, Trebicka, Jonel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318926/
https://ncbi.nlm.nih.gov/pubmed/34337369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2021.100316
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