Loading...

Combining flavin photocatalysis with parallel synthesis: a general platform to optimize peptides with non-proteinogenic amino acids

Most peptide drugs contain non-proteinogenic amino acids (NPAAs), born out through extensive structure–activity relationship (SAR) studies using solid-phase peptide synthesis (SPPS). Synthetically laborious and expensive to manufacture, NPAAs also can have poor coupling efficiencies allowing only a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Immel, Jacob R., Chilamari, Maheshwerreddy, Bloom, Steven
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society of Chemistry 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317666/
https://ncbi.nlm.nih.gov/pubmed/34377401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc02562g
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!