A carregar...
Desymmetrization of pibrentasvir for efficient prodrug synthesis
A novel and practical desymmetrization tactic is described to access a new class of pibrentasvir prodrugs. The homotopic benzimidazoles of pibrentasvir (PIB) are differentiated via a one-pot di-Boc/mono-de-Boc selective N-Boc protection and formaldehyde adduct formation sequence, both enabled by cry...
Na minha lista:
| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society of Chemistry
2021
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8317637/ https://ncbi.nlm.nih.gov/pubmed/34349971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc02396a |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|