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Anti-Mesothelin Recombinant Immunotoxin Therapy for Colorectal Cancer

MICROABSTRACT: Mesothelin (MSLN) is expressed at high levels on the surface of colorectal carcinoma cells, mesothelioma and pancreatic, ovarian and gastric cancer. Immunotoxins targeting MSLN can kill colorectal cancer cell lines in vitro and can inhibit growth and cause regressions in mice. Combina...

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Bibliographic Details
Published in:Clin Colorectal Cancer
Main Authors: Cerise, Adam, Bera, Tapan K, Liu, Xiufen, Wei, Junxia, Pastan, Ira
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317202/
https://ncbi.nlm.nih.gov/pubmed/31345777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2019.06.006
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