Optimization of acetazolamide-based scaffold as potent inhibitors of vancomycin-resistant Enterococcus

Vancomycin-resistant enterococci (VRE) are the second leading cause of hospital-acquired infections (HAIs) attributed to a drug-resistant bacterium in the United States and resistance to the frontline treatments is well documented. To combat VRE, we have repurposed the FDA-approved carbonic anhydras...

詳細記述

保存先:
書誌詳細
出版年:J Med Chem
主要な著者: Kaur, Jatinder, Cao, Xufeng, Abutaleb, Nader S., Elkashif, Ahmed, Graboski, Amanda L., Krabill, Aaron D., AbdelKhalek, Ahmed Hassan, An, Weiwei, Bhardwaj, Atul, Seleem, Mohamed N., Flaherty, Daniel P.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317130/
https://ncbi.nlm.nih.gov/pubmed/32787141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00734
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