Structure-activity relationship studies of acetazolamide-based carbonic anhydrase inhibitors with activity against Neisseria gonorrhoeae

Neisseria gonorrhoeae is an urgent threat to public health in the United States and around the world. Many of the current classes of antibiotics to treat N. gonorrhoeae infection are quickly becoming obsolete due to increased rates of resistance. Thus, there is a critical need for alternative antimi...

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Pubblicato in:ACS Infect Dis
Autori principali: Hewitt, Chad S., Abutaleb, Nader S., Elhassanny, Ahmed E. M., Nocentini, Alessio, Cao, Xufeng, Amos, Devon P., Youse, Molly S., Holly, Katrina J., Marapaka, Anil, An, Weiwei, Kaur, Jatinder, Krabill, Aaron D., Elkashif, Ahmed, Elgammal, Yehia, Graboski, Amanda L., Supuran, Claudiu T., Seleem, Mohamed N., Flaherty, Daniel P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317129/
https://ncbi.nlm.nih.gov/pubmed/33765392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.1c00055
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