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Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension

Hypertension is associated with oxidative stress and perivascular inflammation, critical contributors to perivascular fibrosis and accelerated vascular ageing. Oxidative stress can promote vascular inflammation, creating options for potential use of NADPH oxidase inhibitors in pharmacological target...

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Bibliografische gegevens
Gepubliceerd in:Pharmacol Res
Hoofdauteurs: Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P., Guzik, T.J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316606/
https://ncbi.nlm.nih.gov/pubmed/33131726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105235
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