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Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension

Hypertension is associated with oxidative stress and perivascular inflammation, critical contributors to perivascular fibrosis and accelerated vascular ageing. Oxidative stress can promote vascular inflammation, creating options for potential use of NADPH oxidase inhibitors in pharmacological target...

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Bibliografske podrobnosti
izdano v:Pharmacol Res
Main Authors: Nosalski, R., Mikolajczyk, T., Siedlinski, M., Saju, B., Koziol, J., Maffia, P., Guzik, T.J.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316606/
https://ncbi.nlm.nih.gov/pubmed/33131726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105235
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