Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci

RATIONALE: Mitral valve prolapse (MVP) is a common valvopathy that leads to mitral insufficiency, heart failure and sudden death. Functional genomic studies in mitral valves are needed to better characterize MVP associated variants and target genes. OBJECTIVE: To establish the chromatin accessibilit...

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Publicado no:Circ Res
Main Authors: Kyryachenko, Sergiy, Georges, Adrien, Yu, Mengyao, Barrandou, Takiy, Guo, Lilong, Bruneval, Patrick, Rubio, Tony, Gronwald, Judith, Baraki, Hassina, Kutschka, Ingo, Aras, Kedar K., Efimov, Igor R., Norris, Russel A., Voigt, Niels, Bouatia-Naji, Nabila
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316483/
https://ncbi.nlm.nih.gov/pubmed/33508947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.317581
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