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Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is caused by germline mutations of PKD1 or PKD2 on one allele and a somatic mutation inactivating the remaining normal allele. However, if and how null ADPKD gene renal epithelial cells affect the biology and function of neighboring cells, includi...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ding, Hao, Li, Linda Xiaoyan, Harris, Peter C., Yang, Junwei, Li, Xiaogang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316472/
https://ncbi.nlm.nih.gov/pubmed/34315885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24799-x
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