The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination

Emerging evidence indicates a fundamental role for the epigenome in immunity. Here, we mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination in humans at the single-cell level. Vaccination against seasonal influenza induced persistently diminished H3K27ac in monocy...

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Publié dans:Cell
Auteurs principaux: Wimmers, Florian, Donato, Michele, Kuo, Alex, Ashuach, Tal, Gupta, Shakti, Li, Chunfeng, Dvorak, Mai, Foecke, Mariko Hinton, Chang, Sarah E., Hagan, Thomas, De Jong, Sanne E., Maecker, Holden T., van der Most, Robbert, Cheung, Peggie, Cortese, Mario, Bosinger, Steven E., Davis, Mark, Rouphael, Nadine, Subramaniam, Shankar, Yosef, Nir, Utz, Paul J., Khatri, Purvesh, Pulendran, Bali
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316438/
https://ncbi.nlm.nih.gov/pubmed/34174187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.05.039
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