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Translating glycolytic metabolism to innate immunity in dendritic cells
Growing evidence supports a role for glycolysis in immune activation. Everts et al. (2014) now show that TLR-mediated stimulation of dendritic cells rapidly induces glycolysis, which regenerates NADPH and TCA intermediates to support fatty acid production. This enhances ER and Golgi membrane synthes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050200/ https://ncbi.nlm.nih.gov/pubmed/24807219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.04.012 |
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