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Targeting the complement system in neuromyelitis optica spectrum disorder

INTRODUCTION: Neuromyelitis optica spectrum disorder (NMOSD) is characterized by central nervous system inflammation and demyelination. In AQP4-IgG seropositive NMOSD, circulating immunoglobulin G (IgG) autoantibodies against astrocyte water channel aquaporin-4 (AQP4) cause tissue injury. Compelling...

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Bibliographic Details
Published in:Expert Opin Biol Ther
Main Authors: Asavapanumas, Nithi, Tradtrantip, Lukmanee, Verkman, Alan S.
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316261/
https://ncbi.nlm.nih.gov/pubmed/33513036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2021.1884223
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