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The RNA Binding Proteins YTHDC1 and FMRP Regulate the Nuclear Export of N(6)-Methyladenosine-Modified Hepatitis B Virus Transcripts and Affect the Viral Life Cycle

YTHDC1 and fragile X mental retardation protein (FMRP) bind N(6)-methyladenosine (m(6)A)-modified RNAs and facilitate their transport to the cytoplasm. Here, we investigated the role of these proteins in hepatitis B virus (HBV) gene expression and life cycle. We have previously reported that HBV tra...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kim, Geon-Woo, Imam, Hasan, Siddiqui, Aleem
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316146/
https://ncbi.nlm.nih.gov/pubmed/33883220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00097-21
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