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Polymorphonuclear Myeloid-Derived Cells That Contribute to the Immune Paralysis Are Generated in the Early Phase of Sepsis via PD-1/PD-L1 Pathway
Immune paralysis is a protracted state of immune suppression following the early/acute inflammatory phase of sepsis. CD11b(+) Gr-1(+) cells induced during sepsis are heterogeneous myeloid-derived cells (MDCs). This study investigated the contribution of MDCs to immune paralysis. Treatment of mice wi...
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| Veröffentlicht in: | Infect Immun |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8316145/ https://ncbi.nlm.nih.gov/pubmed/33753411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00771-20 |
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