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A Bioinformatics Whole-Genome Sequencing Workflow for Clinical Mycobacterium tuberculosis Complex Isolate Analysis, Validated Using a Reference Collection Extensively Characterized with Conventional Methods and In Silico Approaches

The use of whole-genome sequencing (WGS) for routine typing of bacterial isolates has increased substantially in recent years. For Mycobacterium tuberculosis (MTB), in particular, WGS has the benefit of drastically reducing the time required to generate results compared to most conventional phenotyp...

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Bibliografiske detaljer
Udgivet i:J Clin Microbiol
Main Authors: Bogaerts, Bert, Delcourt, Thomas, Soetaert, Karine, Boarbi, Samira, Ceyssens, Pieter-Jan, Winand, Raf, Van Braekel, Julien, De Keersmaecker, Sigrid C. J., Roosens, Nancy H. C., Marchal, Kathleen, Mathys, Vanessa, Vanneste, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316078/
https://ncbi.nlm.nih.gov/pubmed/33789960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00202-21
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