In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa

QPX7728 is an ultrabroad-spectrum beta-lactamase inhibitor with potent inhibition of key serine and metallo beta-lactamases. QPX7728 enhances the potency of multiple beta-lactams in beta-lactamase-producing Enterobacterales and Acinetobacter spp. In this study, we evaluated the in vitro activity of...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lomovskaya, Olga, Rubio-Aparicio, Debora, Nelson, Kirk, Sun, Dongxu, Tsivkovski, Ruslan, Castanheira, Mariana, Lindley, Jill, Loutit, Jeffery, Dudley, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315991/
https://ncbi.nlm.nih.gov/pubmed/33782010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00210-21
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