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Tax Induces the Recruitment of NF-κB to Unintegrated HIV-1 DNA To Rescue Viral Gene Expression and Replication

We previously reported that the normally essential step of integration of the HIV-1 proviral DNA intermediate into the host cell genome becomes dispensable in T cells that express the human T cell leukemia virus 1 (HTLV-1) Tax protein, a known activator of cellular NF-κB. The rescue of integrase (IN...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Irwan, Ishak D., Cullen, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315925/
https://ncbi.nlm.nih.gov/pubmed/33883218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00285-21
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