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Data integration uncovers the metabolic bases of phenotypic variation in yeast

The relationship between different levels of integration is a key feature for understanding the genotype-phenotype map. Here, we describe a novel method of integrated data analysis that incorporates protein abundance data into constraint-based modeling to elucidate the biological mechanisms underlyi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Petrizzelli, Marianyela Sabina, de Vienne, Dominique, Nidelet, Thibault, Noûs, Camille, Dillmann, Christine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315545/
https://ncbi.nlm.nih.gov/pubmed/34264947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1009157
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