Structural Deformation of MTX Induced by Nanodrug Conjugation Dictate Intracellular Drug Transport and Drug Efficacy

BACKGROUND: Understanding structural interactions between the active drug and conjugated nanoparticles is critical for optimizing intracellular drug transport and for increasing nano drug efficacy. In this regard, analyzing the conformational deformation of conjugated drugs surrounding nanoparticles...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Park, Jun-Young, Hyun, Ja-Shil, Jee, Jun-Goo, Park, Sung Jean, Khang, Dongwoo
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315289/
https://ncbi.nlm.nih.gov/pubmed/34326636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S317231
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