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Covalent, Non-Covalent, Encapsulated Nanodrug Regulate the Fate of Intra- and Extracellular Trafficking: Impact on Cancer and Normal Cells

Drugs need to be designed to access the designated intracellular organelle compartments in order to maximize anticancer efficacy. This study identified that covalently conjugated, non-covalent polyethylene glycol coated and encapsulated nanodrugs selectively influence drug uptake, the intracellular...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kim, Sang-Woo, Lee, Yeon Kyung, Kim, Sang-Hyun, Park, Jun-Young, Lee, Dong Un, Choi, Jungil, Hong, Jeong Hee, Kim, Sanghyo, Khang, Dongwoo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526881/
https://ncbi.nlm.nih.gov/pubmed/28743942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06796-7
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