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To Knot or Not to Knot: Multiple Conformations of the SARS-CoV-2 Frameshifting RNA Element
The SARS-CoV-2 frameshifting RNA element (FSE) is an excellent target for therapeutic intervention against Covid-19. This small gene element employs a shifting mechanism to pause and backtrack the ribosome during translation between Open Reading Frames 1a and 1b, which code for viral polyproteins. A...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8315264/ https://ncbi.nlm.nih.gov/pubmed/34283611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c03003 |
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