Resistance-Conferring Mutations on Whole-Genome Sequencing of Fluoroquinolone-resistant and -Susceptible Mycobacterium tuberculosis Isolates: A Proposed Threshold for Identifying Resistance

BACKGROUND: Fluoroquinolone resistance in Mycobacterium tuberculosis (Mtb) is conferred by DNA gyrase mutations, but not all fluoroquinolone-resistant Mtb isolates have mutations detected. The optimal allele frequency threshold to identify resistance-conferring mutations by whole-genome sequencing i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Infect Dis
Main Authors: Maruri, Fernanda, Guo, Yan, Blackman, Amondrea, van der Heijden, Yuri F, Rebeiro, Peter F, Sterling, Timothy R
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Major Articles and Commentaries
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315129/
https://ncbi.nlm.nih.gov/pubmed/32348473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciaa496
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker