N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal peptide application

Active c-Src non-receptor tyrosine kinase localizes to the plasma membrane via N-terminal lipid modification. Membranous c-Src causes cancer initiation and progression. Even though transmembrane 4 L six family member 5 (TM4SF5), a tetraspan(in), can be involved in this mechanism, the molecular and s...

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Bibliografische gegevens
Gepubliceerd in:Theranostics
Hoofdauteurs: Song, Haeng Eun, Lee, Yoonji, Kim, Eunmi, Cho, Chang Yun, Jung, Oisun, Lee, Doohyung, Lee, Eun Goo, Nam, Seo Hee, Kang, Minkyung, Macalino, Stephani Joy Y., Kim, Ji Eon, Jung, Jae Woo, Kwon, Sung Won, Choi, Sun, Lee, Jung Weon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2021
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315060/
https://ncbi.nlm.nih.gov/pubmed/34335982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.58739
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