SIRT1 Alleviates Aldosterone-Induced Podocyte Injury by Suppressing Mitochondrial Dysfunction and NLRP3 Inflammasome Activation

BACKGROUND: Podocyte injury contributes to progressive glomerulosclerosis. Previously, we demonstrated the important role of the NLR family pyrin domain containing 3 (NLRP3) inflammasome in mediating the podocyte injury induced by aldosterone. Silent mating type information regulation 2 homolog 1 (S...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Kidney Dis (Basel)
Egile Nagusiak: Jiang, Mingzhu, Zhao, Min, Bai, Mi, Lei, Juan, Yuan, Yanggang, Huang, Songming, Zhang, Yue, Ding, Guixia, Jia, Zhanjun, Zhang, Aihua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: S. Karger AG 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8314781/
https://ncbi.nlm.nih.gov/pubmed/34395544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000513884
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