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TLR2 deficiency promotes IgE and inhibits IgG1 class-switching following ovalbumin sensitization
BACKGROUND: To explore the roles of Toll-like receptor (TLR)2 in Th2 cytokine production and immunoglobulin (Ig) class switching following ovalbumin (OVA) sensitization. METHODS: TLR2(−/−) and wild-type C57BL/6 mice were sensitized by intraperitoneal injection with OVA. Lung pathology was assessed b...
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| Pubblicato in: | Ital J Pediatr |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8314519/ https://ncbi.nlm.nih.gov/pubmed/34315511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13052-021-01088-3 |
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