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Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons
Pathogenic variants in SPG11 are the most frequent cause of autosomal recessive complicated hereditary spastic paraplegia (HSP). In addition to spastic paraplegia caused by corticospinal degeneration, most patients are significantly affected by progressive weakness and muscle wasting due to alpha mo...
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| 出版年: | Front Neurosci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8314181/ https://ncbi.nlm.nih.gov/pubmed/34326717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.680572 |
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