Pharmacokinetics, Urinary Excretion, and Pharmaco-Metabolomic Study of Tebipenem Pivoxil Granules After Single Escalating Oral Dose in Healthy Chinese Volunteers

Tebipenem pivoxil (TBPM-PI), an oral carbapenem antibiotic, has shown special advantages in pediatric infections and was in urgent need in China. Although pharmacokinetics, urinary excretion, and metabolite information of its active form tebipenem (TBPM) has been reported, ethnic differences may exi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Zeyun, Su, Mei, Cheng, Weiyan, Xia, Jueyu, Liu, Shuaibing, Liu, Ruijuan, Sun, Suke, Feng, Luyao, Zhu, Xueya, Zhang, Xiaojian, Tian, Xin, Qu, Lingbo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8314177/
https://ncbi.nlm.nih.gov/pubmed/34326771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.696165
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