Pioglitazone Reverses Alcohol-Induced Alveolar Macrophage Phagocytic Dysfunction

Alcohol use disorders (AUD) increase susceptibility to respiratory infections by 2- to 4-fold in part because of impaired alveolar macrophage (AM) immune function. Alcohol causes AM oxidative stress, diminishing AM phagocytic capacity and clearance of microbes from the alveolar space. Alcohol increa...

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Bibliographic Details
Published in:J Immunol
Main Authors: Yeligar, Samantha M., Mehta, Ashish J., Harris, Frank L., Brown, Lou Ann S., Hart, C. Michael
Format: Artigo
Language:Inglês
Published: AAI 2021
Subjects:
Immune Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313011/
https://ncbi.nlm.nih.gov/pubmed/34193599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000565
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