Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases

Chronic alcohol abuse increases lung oxidative stress and susceptibility to respiratory infections by impairing alveolar macrophage (AM) function. NADPH oxidases (Nox) are major sources of reactive oxygen species in AMs. We hypothesized that treatment with the critical antioxidant glutathione (GSH)...

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Detaylı Bibliyografya
Asıl Yazarlar: Yeligar, Samantha M., Harris, Frank L., Hart, C. Michael, Brown, Lou Ann S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2014
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949056/
https://ncbi.nlm.nih.gov/pubmed/24441868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00159.2013
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