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Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases

Chronic alcohol abuse increases lung oxidative stress and susceptibility to respiratory infections by impairing alveolar macrophage (AM) function. NADPH oxidases (Nox) are major sources of reactive oxygen species in AMs. We hypothesized that treatment with the critical antioxidant glutathione (GSH)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yeligar, Samantha M., Harris, Frank L., Hart, C. Michael, Brown, Lou Ann S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949056/
https://ncbi.nlm.nih.gov/pubmed/24441868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00159.2013
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