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Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases

Chronic alcohol abuse increases lung oxidative stress and susceptibility to respiratory infections by impairing alveolar macrophage (AM) function. NADPH oxidases (Nox) are major sources of reactive oxygen species in AMs. We hypothesized that treatment with the critical antioxidant glutathione (GSH)...

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Bibliografiset tiedot
Päätekijät: Yeligar, Samantha M., Harris, Frank L., Hart, C. Michael, Brown, Lou Ann S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949056/
https://ncbi.nlm.nih.gov/pubmed/24441868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00159.2013
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