Aging-dependent loss of GAP junction proteins Cx46 and Cx50 in the fiber cells of human and mouse lenses accounts for the diminished coupling conductance

The homeostasis of the ocular lens is maintained by a microcirculation system propagated through gap junction channels. It is well established that the intercellular communications of the lens become deteriorative during aging. However, the molecular basis for this change in human lenses has not bee...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Gong, Xiao-Dong, Wang, Yan, Hu, Xue-Bin, Zheng, Shu-Yu, Fu, Jia-Ling, Nie, Qian, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Xiao, Yuan, Gao, Qian, Bai, Yue-Yue, Liu, Yi-Zhi, Li, David Wan-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312418/
https://ncbi.nlm.nih.gov/pubmed/34226295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203247
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