Cocaine-induced increases in motivation require 2-arachidonoylglycerol mobilization and CB1 receptor activation in the ventral tegmental area

A wide body of evidence supports an integral role for mesolimbic dopamine (DA) in motivated behavior. In brief, drugs that increase DA in mesolimbic terminal regions, like cocaine, enhance motivation, while drugs that decrease DA concentration reduce motivation. Data from our laboratory and others s...

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Publicado en:Neuropharmacology
Main Authors: Engi, Sheila A., Beebe, Erin J., Ayvazian, Victoria M., Cruz, Fabio C., Cheer, Joseph F., Wenzel, Jennifer M., Zlebnik, Natalie E.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312311/
https://ncbi.nlm.nih.gov/pubmed/34058192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2021.108625
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