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Variation in the Evolution and Sequences of Proglucagon and the Receptors for Proglucagon-Derived Peptides in Mammals

The mammalian proglucagon gene (Gcg) encodes three glucagon like sequences, glucagon, glucagon-like peptide-1 (GLP-1), and glucagon-like peptide-2 that are of similar length and share sequence similarity, with these hormones having cell surface receptors, glucagon receptor (Gcgr), GLP-1 receptor (Gl...

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Pubblicato in:Front Endocrinol (Lausanne)
Autore principale: Irwin, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312260/
https://ncbi.nlm.nih.gov/pubmed/34322093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.700066
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