Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells

Neuroendocrine (NE) cells are epithelial cells that possess many of the characteristics of neurons, including the presence of secretory vesicles and the ability to sense environmental stimuli. The normal physiologic functions of solitary airway NE cells remain a mystery. We show that mouse and human...

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Опубликовано в: :Science
Главные авторы: Shivaraju, Manjunatha, Chitta, Udbhav K., Grange, Robert M. H., Jain, Isha H., Capen, Diane, Liao, Lan, Xu, Jianming, Ichinose, Fumito, Zapol, Warren M., Mootha, Vamsi K., Rajagopal, Jayaraj
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312065/
https://ncbi.nlm.nih.gov/pubmed/33384370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aba0629
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