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Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells

Neuroendocrine (NE) cells are epithelial cells that possess many of the characteristics of neurons, including the presence of secretory vesicles and the ability to sense environmental stimuli. The normal physiologic functions of solitary airway NE cells remain a mystery. We show that mouse and human...

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Publicat a:Science
Autors principals: Shivaraju, Manjunatha, Chitta, Udbhav K., Grange, Robert M. H., Jain, Isha H., Capen, Diane, Liao, Lan, Xu, Jianming, Ichinose, Fumito, Zapol, Warren M., Mootha, Vamsi K., Rajagopal, Jayaraj
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312065/
https://ncbi.nlm.nih.gov/pubmed/33384370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aba0629
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